NASH: a link between intestinal microbes and "foie gras" syndrome discovered

A recent international study reveals a link between microbiota and NASH. Encouraging results both for screening for this liver disease that affects more and more people, than for its management and treatment.

NASH, or nonalcoholic steatohepatitis, is a liver disease that is affecting more and more people overweight, obese, with diabetes or hypertension. The figures, which are constantly increasing, are worrying health professionals, because the "fatty liver" syndrome can lead to cirrhosis or liver cancer.

Problem, to date, no treatment has yet been found to cure this silent disease, which causes almost no symptoms, which often delays the diagnosis.

The only way to act effectively is to change your lifestyle and your eating habits: losing weight, following a proper low calorie diet, and regular physical activity.

Recently, a team of French, Italian and English researchers would have made an encouraging discovery to allow an earlier diagnosis of the disease: some intestinal bacteria, present in our microbiota, could be markers of the disease.

In fact, by analyzing the medical data of 800 obese patients, the researchers noticed the presence of a high level of phenylacetic acid in people affected by NASH. Identifying these markers in the gut microbiota may therefore allow earlier diagnosis and therefore more effective management of the disease.

The team, whose work was published in the journal Nature Medicine, intends to continue its research on probiotic screening and treatment of NASH.

Video: Your Microbiome and Your Brain (November 2019).


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